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Taltz ® (ixekizumab)
This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information. For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: www.medicines.org.uk (England, Scotland, Wales) or www.emcmedicines.com/en-GB/northernireland/ (Northern Ireland).
Can Taltz® (ixekizumab) be used in Patients with COVID-19?
Lilly has not studied the use of ixekizumab in patients with comorbid COVID-19 nor in patients at risk of contracting COVID-19.
Ixekizumab Treatment in Patients with Suspected or Confirmed COVID-19
Ixekizumab should not be used during active COVID-19 infection and may be resumed after medical consultation and infection is resolved.1
- If COVID-19 is confirmed, ixekizumab should be immediately discontinued and may be resumed after medical consultation and infection is resolved.1
- If COVID-19 infection is suspected and signs and symptoms of acute infection occur, the patient should consult with their healthcare provider and seek medical advice for guidance on continuing and initiating ixekizumab treatment.1
Use of Ixekizumab in High Risk Areas
At this time, Eli Lilly and Company has not studied the use of ixekizumab in patients at risk of contracting COVID-19.
The decision on treatment remains at the discretion of prescribing physician.
COVID-19
COVID-19 is an active respiratory infection, which is typically mild and may also lead to acute respiratory distress syndrome which can be lethal.1
Infectious Disease Resources
For the most current information regarding the coronavirus, please refer to the World Health Organization (WHO) website:
Ixekizumab Infection-Related Warnings and Precautions according to the SmPC
Ixekizumab is contraindicated in patients with clinically important active infections (e. g. active tuberculosis).2
Treatment with ixekizumab is associated with an increased rate of infections such as upper respiratory tract infection, oral candidiasis, conjunctivitis, and tinea infections.2
Ixekizumab should be used with caution in patients with clinically important chronic infection or a history of recurrent infection. Patients should be instructed to seek medical advice if signs or symptoms suggestive of an infection occur. If an infection develops, monitor carefully and discontinue ixekizumab if the patient is not responding to standard therapy or the infection becomes serious. Ixekizumab should not be resumed until the infection resolves.2
For further information please refer to the Taltz SmPC.
References
1Data on file, Eli Lilly and Company and/or one of its subsidiaries.
2Taltz [summary of product characteristics]. Eli Lilly and Company (Ireland) Limited, Ireland
Date of Last Review: 03 March 2023